Dotmatics
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    Scientific Intelligence Platform

    AI-powered data management and workflow automation for multimodal scientific discovery

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    Capabilities

    Adaptive Workflows

    Customize, automate, and scale your lab workflows

    Artificial Intelligence

    Leverage AI and ML to accurately predict scientific outcomes

    Material & Ontology Management

    Classify materials and manage entities with full traceability

    Luma Products

    BioGlyph Luma

    Next-gen protein design for complex biologics – integrating molecular modeling, registration, and production with seamless data traceability and precision.

    FCS Express Luma

    Streamlined flow cytometry data capture and traceability—connecting FCS Express outputs to the centralized Luma platform.

    Geneious Luma

    Accelerated antibody discovery for sequence analysis, construct design, and lab execution—integrating the power of Geneious Prime and Geneious Biologics with Luma’s adaptive workflows.

    Lab Connect

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    The State of Chemicals & Materials

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    Antibody & Protein Engineering

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    Flow Cytometry

    Automated flow data processing and auto-gating

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Dotmatics
Request Demo
  • Platform

    Scientific Intelligence Platform

    AI-powered data management and workflow automation for multimodal scientific discovery

    Learn More

    Capabilities

    Adaptive Workflows

    Customize, automate, and scale your lab workflows

    Artificial Intelligence

    Leverage AI and ML to accurately predict scientific outcomes

    Material & Ontology Management

    Classify materials and manage entities with full traceability

    Luma Products

    BioGlyph Luma

    Next-gen protein design for complex biologics – integrating molecular modeling, registration, and production with seamless data traceability and precision.

    FCS Express Luma

    Streamlined flow cytometry data capture and traceability—connecting FCS Express outputs to the centralized Luma platform.

    Geneious Luma

    Accelerated antibody discovery for sequence analysis, construct design, and lab execution—integrating the power of Geneious Prime and Geneious Biologics with Luma’s adaptive workflows.

    Lab Connect

    Automated lab data ingestion and modeling—connect instruments, structure scientific data, and streamline lab operations with seamless integration.

  • Solutions

    The State of Chemicals & Materials

    Uncover key trends shaping the chemicals and materials industry

    Read More

    Solutions

    Antibody & Protein Engineering

    Integrated registration, lab workflow and data management

    Flow Cytometry

    Automated flow data processing and auto-gating

    Industry

    Biology Discovery

    Chemistry R&D

    Chemicals and Materials

  • Products

    R&D Software for Scientists

    Review our comprehensive portfolio of products driving scientific breakthroughs for R&D innovation and collaboration.

    Explore All

    BIOINFORMATICS

    SnapGene

    Geneious Prime

    Geneious Biologics

    CHEMINFORMATICS

    Vortex

    DATA ANALYSIS & VISUALIZATION

    Prism

    ELN

    ELN & Data Discovery Platform

    FLOW CYTOMETRY

    OMIQ

    FCS Express

    MULTIMODAL SCIENCE

    Scientific Intelligence Platform

    PROTEOMICS

    Protein Metrics

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    Watch a Demo

    See Dotmatics in action with on-demand product tours and demos.

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    Latest insights and perspectives to lead your R&D

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End-to-End Flow Cytometry Optimization

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Introduction: Modern Tools, Manual Data Handling

Despite incredible advances in flow cytometry software and instrumentation, a major hurdle has continued to haunt many researchers—moving data across the research workflow. In order to progress from initial idea to actionable insights, researchers must transition through a series of steps, including:

  • Designing and optimizing panels (including for high-dimensional assays) 

  • Planning and requesting experiments using an ELN/LIMS 

  • Acquiring raw results data from instruments

  • Performing classical and modern flow data analysis with specialty software

  • Storing, parsing, and converting results 

  • Modeling and visualizing flow data 

  • Integrating and contextualizing data with ancillary sources, such as clinical data

To move through these key research stages, teams often need to manually handle data as they navigate a labyrinth of software, instruments, external systems, siloed data sources, files shares, and spreadsheets. This not only wastes time and risks error, but it also makes it difficult to uncover insights and make connections. While some quick fixes, like JSON conversion, can help with collecting and standardizing instrument data, this early workflow optimization still leaves researchers struggling to perform advanced analyses and attain deeper contextualization later in the research workflow. The bottom line is that dataflows are hindering workflows. Dotmatics is changing this paradigm.  

Optimizing Workflows by Facilitating Dataflows

By addressing the disconnect between complex workflows and manual dataflows, flow cytometry teams can optimize their analysis like never before possible. Dotmatics is helping facilitate this transformative change by providing core technology that unites the broad range of instruments, data, and specialty software needed in modern flow cytometry analysis. The synergistic Dotmatics flow cytometry analysis solution minimizes manual data handling, automates repetitive steps, and delivers clean, organized, well-tagged, FAIR-compliant data right alongside the advanced analysis tools experts need to scrutinize data and drive research decisions. 

Luma and OMIQ Integration:
A Synergistic Solution for End-to-End Optimization

By integrating essential technologies needed in modern flow cytometry analysis, Dotmatics is helping researchers optimize the entirety of their analysis workflows, not just bits and pieces. Key amongst these integrated technologies are:

  • the AI-powered Luma data management platform that facilitates instrument integration, data acquisition and processing, and workflow/dataflow automation

  • the OMIQ cloud-based cytometry analysis platform that offers classical manual analysis alongside 30+ natively-integrated advanced algorithms, autogating functionality, and customizable analytical workflows that are shareable, automatable, and auditable 

These two trusted products form the core of the integrated Dotmatics flow cytometry solution, which enables:

  • integration of data management and analysis tools (e.g., classical, advanced, statistical, sequence) on a bi-directional platform that is built on Databricks

  • automated instrument data uploads with intelligent parsing

  • customizable metadata tagging of FCS files

  • creation of a searchable, scalable repository of interoperable FAIR-compliant data 

  • contextualization of cytometry results with ancillary data (e.g., experiment, patient, clinical, and genomics data) 

  • seamless dataflow across an auditable end-to-end research workflow

With these capabilities, researchers are empowered to more quickly progress through the myriad of steps needed to transform raw cytometry results data into the informed insights that drive decision making. 

OMIQ Luma workflow


Figure 1:
Dotmatics helps experts move beyond disjointed workflows and manual data handling. With OMIQ integrated onto the Luma data platform, researchers can seamlessly access, analyze, and contextualize well-tagged cytometry data in order to drive research decisions. 

On-Demand Webinar: Rethinking Flow Cytometry - Eliminating Manual Data Handling with the Luma and OMIQ Integration

Want to learn more about this powerful new approach to optimizing flow cytometry analysis? Watch the on-demand webinar: Rethinking Flow Cytometry - Eliminating Manual Data Handling with the Luma and OMIQ Integration.

Topics explored include:

  • Manual data handling pitfalls that slow down and compromise cytometry analysis

  • Automated analysis benefits, including improved efficiency and reduced human error

  • Instrument and software options to accelerate data transfers and decision making

  • Dotmatics’ end-to-end integrated solution that streamlines the entire cytometry analysis process by enabling automatic instrument data uploads, intelligent metadata tagging, autogating, and in-depth cytometry and statistical analyses

Real-time demos are given to illustrate how the integrated Dotmatics flow cytometry solution helps optimize, and where possible automate, the specific workflow steps needed to:

  • Gather results data for analysis

  • Supplement with experimental metadata (e.g., compound, sample, concentration, and target data in preparation for dose-response analysis)

  • Run advanced cytometry analysis workflows with OMIQ (e.g., autogating)

  • Export results to further exploration (e.g., Prism statistical analysis)

Presenters include:

  • Phil Mounteny (Regional VP, Science & Technology, Dotmatics) - Phil holds a PhD in Polymer Chemistry. He has extensive history working at the intersection of science and technology. At Dotmatics, Phil previously led the North American application scientist team, where he focused on pre-sales, delivery, and client management.  Now serving as Dotmatics’ Regional VP of Science and Technology, Phil often works closely with customers to perform consultations, system analyses, and business practice assessment in order to help Dotmatics deliver solutions that meet real market needs.
     

  • Julia Prier (Senior Product Manager, OMIQ) - Julia has a PhD from the University of Melbourne and she conducted postdoctoral research in collaboration with the Agency for Science, Technology and Research (A*Star) in Singapore. Her work combined flow cytometry, sequencing, and machine learning to understand cells critical for defense against cancer and viruses. During her 10+ years in the laboratory in the fields of immunology and virology, she gained experience in the broad areas of molecular biology, cell biology, and bioinformatics.


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